thalassemia oral manifestations
TT patients had significantly higher frequencies of all oral manifestations than healthy controls p 0001 for all in which burning sensation of oral mucosa 908 lingual varicosity 908. 2 gingivitis 82 was very high in the study group.
Oral surgery oral medicine and oral pathology The signs symptoms and potential complications of the thalassemias are discussed.
. A CASE REPORT OF ORAL AND MAXILLOFACIAL MANIFESTATION FROM POPULATION OF KARACHI PAKISTAN S. The main oral manifestations of thalassemia are Class II malocclusion maxillary protrusion high caries index severe gingivitis. Caution should be exercised in thalassemia patients due to complications related to compromised immunity and cardiovascular.
Any dental surgical procedure for such patients should be done under antibiotic cover and immediately after transfusion. Swollen bleeding gums. In this study 65 TT patients were collected from the thalassemia center at the Women and Children Hospital in Ramadi.
A total of 38 Emirati children with beta thalassaemia major mean age 1018 319 and 76 healthy Emirati children mean age 1079 354 were recruited from Dubai Genetic Thalassaemia. Caution should be exercised in thalassemia patients due to complications related to compromised immunity and cardiovascular issues. Their oral manifestations including burning sensation and numbness of oral mucosa dry mouth dysfunction of taste lingual varicosity AG recurrent aphthous ulcerations RAU and oral lichen planus OLP complete blood count and blood chemistry including blood levels of Hb iron vitamin B12 folic acid and homocysteine were inquired examined and recorded.
Necrotising stomatitis possibly linked to agranulocytosis due to deferiprone has also been described in thalassaemia Tewari et 2009. Facial and dental abnormalities include marked opened. Thalassemia signs and symptoms can include.
Any d ental surgical p rocedure for suc h patie nts s hould b e. A case of thalassemia minor is presented with emphasis on how the condition may affect the dental management of the patient. Thalassemia is an autosomal recessive hemoglobinopathy that originated in the Mediterranean region.
The facial expression of homozygous β-thalassemia J. Oral thrush is also common in infants due to poor oral hygiene. The purpose of this study was to identify special oral and dentofacial manifestations peculiar to beta thalassaemia major children in Dubai United Arab Emirates UAE.
Fatigue Weakness Pale or yellowish skin Facial bone deformities Slow growth Abdominal swelling Dark urine Some babies show signs and symptoms of thalassemia at birth. 4 severity of disease. 1 94 of thalassemia patients showed oral and maxillofacial manifestations which confirmed the results of other workers.
The oral manifestations that collected include the following. These data were compared with. Dental and jaw pain pallor oral mucosa oral ulceration and burning tongue may also be present secondary to chronic anaemia.
To date no specific oral manifestations of thalassemia patients has been found for either - -thalassemia or even the proportion of patients who have these manifestations. Man Medicine 1990 27 β THALASSEMIA. However close dental and orthodontic monitoring is crucial.
The teeth can be significantly affected in patients with thalassemia but proper transfusion therapy can prevent many of the changes. Dry mouth dysfunction of taste burning. The genetic defect causes a reduction in the rate of globin chain synthesis which causes the formation of abnormal hemoglobin molecules.
The resultant microcytic anemia is the characteristic presenting symptom of the thalassemias. Thalassemia is an inherited blood disorder in pakistan no work on oral and maxillofcial manifestation of thalassemia in pakistan dr syed muhammad ali start work on oral and maxillofacial under the supervision of eminent proffessor of oral and maxillofacial surgery prof dr syed mahmood haider this work is the attemp in dentistry in pakistan on. From the present study authors concluded the followings.
Any dental surgical procedure for such patients should be done under antibiotic cover and immediately after transfusion. In addition to regular annual dental care thalassemia patients should be evaluated by a dentist to determine if bony changes requiring orthodontic treatments have developed. TT patients had significantly higher frequencies of all oral manifestations than healthy controls p 0001 for all in which burning sensation of oral mucosa 908 lingual varicosity 908 dry mouth 723 atrophic glossitis 323 and numbness of the oral mucosa 308 were the five leading oral manifestations for TT patients.
Vichinsky Author Affiliations Department of HematologyOncology Childrens Hospital Research Center Oakland Oakland California 94609 Correspondence. Iron-deficiency anemia and folic acid deficiency may produce symptoms of glossodynia and loss of papillae on the tongue similar to those seen in the patient whose case is presented here23 the hematologic findings in thalassemia minor are very similar to. Vichinsky Department of HematologyOncology Childrens Hospital Research Center Oakland Oakland California 94609 Correspondence.
If orthodontics are recommended they will. The main oral manifestations of thalassemia are Class II malocclusio n maxillary pr otrusion high caries index severe gingivitis. Ali Syed Mahmood Haider Medicine 2017 TLDR.
Iron-deficiency anemia and folic acid deficiency may produce symptoms of glossodynia and loss of papillae on the tongue similar to those seen in the patient whose case is presented here23 the hatologie findings in thalassemia minor are very similar to those of iron-deficiency anemia3 and folic acid deficiency is a common complication of. Moreover TT patients had significantly lower mean. Others develop them during the first two years of life.
Occlusal abnormalities and bimaxillary protrusions are frequent in patients with thalassemia major. Dental Manifestations in Thalassemia Patients The orofacial manifestations of thalassemia are due to the bony changes called Cooley facies caused by ineffective erythropoiesis along with the development of bone-expanding erythroid masses Figure 1. Individuals with thalassemia have variable degrees of anemia and extramedullary hematopoiesis which in turn can cause bone changes impaired growth and iron overload.
Clinical Manifestations of a-Thalassemia Elliott P. Immune compromised patient are more likely to suffer from xerostomia candidiasis oral thrush. The main oral manifestations of thalassemia are Class II malocclusion maxillary protrusion high caries index severe gingivitis.
3 most of the children were habitual betel betel nut and gutkta chewer from the early age. Thalassemia Oral Manifestations Bimaxillary hyperplasia. Clinical Manifestations of α-Thalassemia Elliott P.
Vitamin deficiency also causes different oral manifestations like Vitamin C deficiency. Thalassemia causes bleeding gums loosened teeth gingivitis. This topic review discusses the clinical manifestations and diagnosis of alpha and beta thalassemia the two most common forms.
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